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PUBLICATIONS

RESEARCH ARTICLES
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  1. Rajput PK, Varghese JF, Srivastava AK, Kumar U, Yadav UCS*. Visfatin-induced upregulation of lipogenesis via EGFR/AKT/GSK3β pathway promotes breast cancer cell growth. Cell Signal. 2023 Jul;107:110686. doi: 10.1016/j.cellsig.2023.110686. 

  2. Sharma JR, Agraval H, Yadav UCS*. Cigarette smoke induces epithelial-to-mesenchymal transition, stemness, and metastasis in lung adenocarcinoma cells via upregulated RUNX-2/ galectin-3 pathway. Life Sci. 2023 Apr 1;318:121480. doi: 10.1016/j.lfs.2023.121480.

  3. Hilal AR, Varghese JF, Dhimmar B, Yadav UCS, Vasita R. Polycaprolactone-collagen nanofibers loaded with dexamethasone and simvastatin as an osteoinductive and immunocompatible scaffold for bone regeneration applications. Biomater Biosyst. 2022 Sep 26; 8: 100064, doi: 10.1016/j.bbiosy.2022.100064

  4. Rajput PK, Sharma JR, Yadav UCS*. Cellular and molecular insights into the roles of visfatin in breast cancer cells plasticity programs. Life Sci. 2022 Sep 1; 304: 120706. doi: 10.1016/j.lfs.2022.120706.

  5. Agraval H, Sharma JR, Prakash N, Yadav UCS*. Fisetin suppresses cigarette smoke extract-induced epithelial to mesenchymal transition of airway epithelial cells through regulating COX-2/MMPs/β-catenin pathway. Chem Biol Interact. 2021 Dec 2; 351: 109771. doi: 10.1016/j.cbi.2021.109771.

  6. Dowarah J, Patel D, Marak BN, Yadav UCS, Shah PK, Shukla PK, Singh VP. Green synthesis, structural analysis and anticancer activity of dihydropyrimidinone derivatives. RSC Adv., 2021, 11, 35737-35753. DOI: 10.1039/D1RA03969E

  7. Lalhruaizela, Patel D, Marak BN, Dowarah J, Sran BS, Yadav UCS, Singh VP. Supramolecular architectures in dihydropyridones: Synthesis, crystal structure, Hirshfeld analysis, cytotoxicity and in silico studies. Journal of Molecular Structure: 1250 (2), 2022, 131671, ISSN 0022-2860, doi.org/10.1016/j.molstruc.2021.131671.

  8. Varghese JF, Patel R, Singh M, Yadav UCS*. Fisetin prevents oxidized low-density lipoproteins induced macrophage foam cell formation. J Cardiovasc Pharmacol. 2021 Nov 1;78(5):e729-e737. doi: 10.1097/FJC.0000000000001096. PMID: 34173812.

  9. Dowarah J, Marak BN, Yadav UCS, Singh VP, Potential drug development and therapeutic approaches for clinical intervention in COVID-19, Bioorganic Chemistry, 2021 May 25; 114, 105016, ISSN 0045-2068, Doi.org/10.1016/j.bioorg.2021.105016.

  10. Yadav UCS*. Vaccines and drugs under clinical trials for prevention and treatment of COVID-19. VirusDis. 2021 March 22; 32(1), 13-19. Doi: 10.1007/s13337-020-00650-7

  11. Atale N, Mishra CB, Kohli S, Mongre RK, Prakash A, Kumari S, Yadav UCS, Jeon R, Rani V. Anti-inflammatory Effects of S. cumini Seed Extract on Gelatinase-B (MMP-9) Regulation against Hyperglycemic Cardiomyocyte Stress. Oxid Med Cell Longev. 2021 Mar 3; 2021: 8839479. Doi: 10.1155/2021/8839479.

  12. Sharma JR, Yadav UCS. COVID-19 severity in obese patients: Potential mechanisms and molecular targets for clinical intervention. Obes Res Clin Pract. 2021 Jan 19:S1871-403X(21)00004-1. doi: 10.1016/j.orcp.2021.01.004.

  13. Dholia N, Sethi GS, Naura AS, Yadav UCS. Cysteinyl leukotriene D4 (LTD4) promotes airway epithelial cell inflammation and remodelling. Inflamm Res. 2021 Jan;70(1):109-126. doi: 10.1007/s00011-020-01416-z. 

  14. Shinde P, Agraval H, Srivastav AK, Yadav UCS, Kumar U. Physico-chemical characterization of carvacrol loaded zein nanoparticles for enhanced anticancer activity and investigation of molecular interactions between them by molecular docking. Int J Pharm. 2020 Oct 15;588:119795. doi: 10.1016/j.ijpharm.2020.119795.

  15. Jangid AK, Agraval H, Gupta N, Jain P, Yadav UCS, Pooja D, Kulhari H Amorphous nano morin outperforms native molecule in anticancer activity and oral bioavailability. Drug Dev Ind Pharm. 2020 Jul;46(7):1123-1132. doi: 10.1080/03639045.2020.1776318.

  16. Rather HA, Patel R, Yadav UCS, Vasita R. Dual drug-delivering polycaprolactone-collagen scaffold to induce early osteogenic differentiation and coupled angiogenesis. Biomed Mater. 2020 May 19;15(4):045008. doi: 10.1088/1748-605X/ab7978.

  17. Saxena N, Agraval H, Barick KC, Ray D, Aswal VK, Singh A, Yadav UCS, Dube CL. Thermal and microwave synthesized SPIONs: Energy effects on the efficiency of nano drug carriers. Mater Sci Eng C Mater Biol Appl. 2020 Jun;111:110792. doi: 10.1016/j.msec.2020.110792.

  18. Prasad N, Sharma JR, Yadav UCS. Induction of growth cessation by acacetin via β-catenin pathway and apoptosis by apoptosis inducing factor activation in colorectal carcinoma cells. Mol Biol Rep.2019; 1-15

  19. Agraval H and Yadav UCS, MMP-2 and MMP-9 mediate cigarette smoke extract-induced epithelial-mesenchymal transition in airway epithelial cells via EGFR/Akt/GSK3β/β-catenin pathway: Amelioration by fisetin. Chem Biol Interact. 2019; 314

  20. Singh M, Kumari B and Yadav UCS, Regulation of oxidized LDL-induced inflammatory process through NLRP3 inflammasome activation by the deubiquitinating enzyme BRCC36. Inflammation Research. 2019 ; 68 1-12.

  21. Patel R, Varghese JF, Singh RP and Yadav UCS, Induction of endothelial dysfunction by oxidized low-density lipoproteins via downregulation of Erk-5/Mef2c/KLF2 signaling: Amelioration by fisetin. Biochimie. 2019 Jun 11;163:152-162.

  22. Patel R, Varghese JF, and Yadav UCS, Hyperglycemia Induced Modulation of eNOS and ICAM-1 in Endothelial Cells by Mek5/Erk5/Klf2 pathway. Int. J. Pharm. Biol. Sci, 2019. 9 (1): 509-516.

  23. Varghese JF, Patel R, Yadav UCS. Sterol regulatory element binding protein (SREBP) -1 mediates oxidized low-density lipoprotein (oxLDL) induced macrophage foam cell formation through NLRP3 inflammasome activation. Cell Signal. 2018;53:316-326. doi: 10.1016/j.cellsig.2018.10.020.

  24. Kumari B and Yadav UCS. Adipokine Visfatin's Role in Pathogenesis of Diabesity and Related Metabolic Derangements. Curr Mol Med. 2018;18(2):116-125. doi: 10.2174/1566524018666180705114131

  25. Prasad N. and Yadav UCS. Anti-Inflammatory Effects of Acacetin in IL-1β induced colon epithelial (CaCO2) Cells.Int J Pharm Biol Sci.2018. ISSN: 2321-3272 (Print), ISSN: 2230-7605 (Online)

  26.  Prasad N., Sabarwal, A., Yadav, U.C.S. et al. Lupeol induces S-phase arrest and mitochondria-mediated apoptosis in cervical cancer cells. J Biosci (2018) 43: 249. https://doi.org/10.1007/s12038-018-9743-8

  27. Dholia N. and Yadav UCS. Lipid mediator Leukotriene D4-induces human airway epithelial cells proliferation through EGFR/ETK1/2 pathway. Prostaglandins and other Lipid Mediators. 2018. doi: 10.1016/j.prostaglandins.2018.05.003

  28. Ramteke P and Yadav UCS. Antiproliferative Effect of Hesperitin in Small Airway Epithelial Cells.Int J Pharm Biol Sci.2018.ISSN: 2230-7605 (Online); ISSN: 2321-3272 (Print)

  29. Varghese JF, Patel R, Yadav UCS* Novel insights in the metabolic syndrome-induced oxidative stress and inflammation-mediated atherosclerosis.Curr Cardiol Rev. 2017 Oct 9. doi: 10.2174/1573403X13666171009112250 

  30. Varghese JF, Patel R, Yadav UC* Metabolic Syndrome: A Forerunner of Cardiovascular Diseases,Edorium J Biochem 2017; 2: 4-6. (Editorial)

  31. Rani V, Deep G, Singh RK, Palle K, Yadav UC. Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies, Life Sci. 2016; 148: 183-93

  32. Yadav UC, Rani V, Deep G, Singh RK, Palle K. Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics, Oxid Med Cell Longev. 2016; 2016: 9137629.(Editorial)

  33. Yadav UC, Srivastava SK. Cysteinyl Leukotrienes (CysLTs): Role in Obesity-Induced Asthma. Curr Mol Med. 2015;15(7):598-605.

  34. Atale N, Gupta S, Yadav UC, Rani V. Cell-death assessment by fluorescent and nonfluorescent cytosolic and nuclear staining techniques. J Microsc. 2014 Jul; 255(1):7-19.

  35. Yadav UC , Baquer NZ. Pharmacological effects of Trigonella foenum-graecum L. in health and disease. Pharm Biol. 2014 Feb; 52(2): 243-54.

  36. Yadav UC , Ramana KV. Endotoxin-induced uveitis in rodents. Methods Mol Biol. 2013; 1031: 155-62.

  37. Yadav UC, Ramana KV, Srivastava SK. Aldose reductase regulates acrolein-induced cytotoxicity in human small airway epithelial cells. Free Radic Biol Med .2013; 65C:15-25.

  38. Yadav UC and Ramana K V. Regulation of NF-B-Induced Inflammatory Signaling by Lipid Peroxidation-Derived Aldehydes," Oxidative Medicine and Cellular Longevity, vol. 2013, Article ID 690545, 2013.

  39. Yadav UC, Naura A, Aguilera-Aguirre L, Boldogh I, Boulares HA, Ramana K V, Srivastava SK. Aldose Reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice. PLoS One; 2013; 8(2): e57442.

  40. Yadav UC, Mishra R, Aguilera-Aguirre L, Sur S, Boldogh I, Ramana K V, Srivastava SK.  Prevention of Allergic Rhinitis by Aldose Reductase Inhibition in a Murine Model. Inflammation & Allergy - Drug Targets; 2013; 12(3):178-86.

  41. Yadav UC, Srivastava SK, Ramana KV. Prevention of VEGF-induced growth and tube formation in human retinal endothelial cells by aldose reductase inhibition. J Diabetes Complications. 2012; 26(5):369-77.

  42. Yadav UC, Aguilera-Aguirre L, Boldogh I, Ramana KV, Srivastava SK. Aldose Reductase Deficiency in Mice Protects from Ragweed Pollen Extract (RWE)-induced Allergic Asthma. Respiratory Research 2011, 12:145

  43. Shoeb M, Yadav UC, Srivastava SK, Ramana KV. Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages. Free Radic Biol Med. 2011 Nov 1;51(9):1686-96.

  44. Yadav UC, Shoeb M, Srivastava SK, Ramana KV. Aldose reductase deficiency protects from autoimmune- and endotoxin -induced uveitis in mice. Invest Ophthalmol Vis Sci. 2011 Oct 17;52(11):8076-85.

  45. Yadav UC, Shoeb M, Srivastava SK, Ramana KV. Amelioration of Experimental Autoimmune Uveoretinitis by Aldose Reductase Inhibition in Lewis Rats. Invest Ophthalmol Vis Sci. 2011 Oct 11;52(11):8033-41.

  46. Ramana KV, Yadav UC, Calhoun WJ, Srivastava SK. Current Prospective of Aldose Reductase Inhibition in the Therapy of Allergic Airway Inflammation in Asthma. Curr Mol Med. 2011 Oct 1;11(7):599-608.

  47. Srivastava SK, Yadav UC, Reddy AB, Saxena A, Tammali R, Mohammad S, Ansari NH, Bhatnagar A, Petrash MJ, Srivastava S, Ramana KV. Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders. Chem Biol Interact. 2011;191(1-3):330-338.

  48. Yadav UC, Ramana KV, Srivastava SK. Aldose reductase inhibition suppresses airway inflammation. Chem Biol Interact. 2011;191(1-3):339-345.

  49. Yadav UC, Kalariya NM, Ramana KV. Emerging Role of Antioxidants in the Protection of Uveitis Complications. Curr Med Chem. 2011;18(6):931-42. Review.

  50. Yadav UC, Aguilera-Aguirre L, Ramana KV, Boldogh I, Srivastava SK. Aldose reductase inhibition prevents metaplasia of airway epithelial cells. PLoS One. 2010 Dec 28;5(12): e14440.

  51. Yadav UC, Srivastava SK, Ramana KV. Understanding the role of aldose reductase in ocular inflammation. Curr Mol Med. 2010;10(6):540-9.

  52. Yadav UC, Kalariya NM, Srivastava SK, Ramana KV. Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages. Free Radic Biol Med. 2010;48(10):1423-34.

  53. Hur KY, Kim SH, Choi MA, Williams DR, Lee YH, Kang SW, Yadav UC, Srivastava SK, Jung M, Cho JW, Kim SG, Kang ES, Lee HC. Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway. Atherosclerosis. 2010;211(1):69-76.

  54. Yadav UC, Srivastava SK, Ramana KV. Inhibition of aldose reductase attenuates endotoxin signals in human non-pigmented ciliary epithelial cells. Exp Eye Res. 2010;90(5):555-63.

  55. Yadav UC, Ramana KV, Naura A, Boulares HA, Boldogh I and Srivastava SK. Aldose Reductase Inhibition Suppresses the Expression of Th2 Cytokines and Airway Inflammation in Ovalbumin-Induced Asthma in Mice. J. Immunol. 2009; 183(7): 4723-4732.

  56. Yadav UC, Ramana KV, Aguilera-Aguirre L, Boldogh I, Boulares HA, Srivastava SK. Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice. PLoS One. 2009; 4(8): e6535.

  57. Yadav UC, Subramanyam S, Ramana KV. Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1. Invest Ophthalmol Vis Sci. 2009; 50(5):2276-2282.

  58. Yadav UC, Ighani-Hosseinabad F, van Kuijk FJ, Srivastava SK, Ramana KV. Prevention of posterior capsular opacification through aldose reductase inhibition. Invest Ophthalmol Vis Sci. 2009; 50(2):752-759.

  59. Yadav UC, Ramana KV, Yogesh C. Awasthi, and Srivastava SK. Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells. Toxicology and Applied Pharmacology. 2008; 227(2):257-264.

  60. Yadav UC, Srivastava SK, Ramana KV. Aldose reductase inhibition prevents endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci. 2007; 48(10): 4634-4642.

  61. Pladzyk A, Reddy AB, Yadav UC, Tammali R, Ramana KV, Srivastava SK. Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells. Invest Ophthalmol Vis Sci. 2006; 47(12):5395-5403.

  62. Ramana KV, Bhatnagar A, Srivastava S, Yadav UC, Awasthi S, Awasthi YC, Srivastava SK. Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth. J Biol Chem. 2006; 281(26):17652-17660.

  63. Moorthy K, Yadav UC, Siddiqui MR, Mantha AK, Basir SF, Sharma D, Cowsik SM, Baquer NZ. Effect of hormone replacement therapy in normalizing age related neuronal markers in different age groups of naturally menopausal rats. Biogerontology. 2005; 6(5):345-56.

  64. Yadav UC, Moorthy K, Baquer NZ. Combined treatment of sodium orthovanadate and Momordica charantia fruit extract prevents alterations in lipid profile and lipogenic enzymes in alloxan diabetic rats. Mol Cell Biochem. 2005; 268(1-2):111-20.

  65. Moorthy K, Yadav UC, Mantha AK, Cowsik SM, Sharma D, Basir SF, Baquer NZ. Estradiol and progesterone treatments change the lipid profile in naturally menopausal rats from different age groups. Biogerontology. 2004; 5(6):411-9.

  66. Moorthy K, Yadav UC, Siddiqui MR, Sharma D, Basir SF, Baquer NZ. Effect of estradiol and progesterone treatment on carbohydrate metabolizing enzymes in tissues of aging female rats. Biogerontology. 2004; 5(4):249-59.

  67. Yadav UC, Moorthy K, Baquer NZ. Effects of sodium-orthovanadate and Trigonella foenum-graecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes. J Biosci. 2004; 29(1):81-91.

  68. Baquer NZ, Sinclair M, Kunjara S, Yadav UC, McLean P. Regulation of glucose utilization and lipogenesis in adipose tissue of diabetic and fat fed animals: effects of insulin and manganese. J Biosci. 2003; 28(2):215-21.

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  BOOKS (EDITED)
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  1. Functional Food and Human Health. Yadav UC and Rani V (Eds), Springer (India) Private Ltd., New Delhi, 2018. ISBN 978-981-13-1123-9 (eBook); DOI: 10.1007/978-981-13-1123-9
  2. Free Radicals in Human Health and Disease: Oxidative Stress and Human Health. Yadav UC, Rani V (Eds), Springer (India) Private Ltd., New Delhi, 2015. ISBN 978-81-322-2034-3; DOI: 10.1007/978-81-322-2035-0
  3. Human Anatomy and physiology, Various contributors, OpenStax College, Rice University, Houston, Texas, 25 April 2013.  ISBN-13: 978-1-938168-13-0
  
BOOK CHAPTERS
  1. Singh M, Sharma JR, Agraval H, Yadav UCS. Inflammation and Its Role in Obesity-Related Complications. In: Faintuch J., Faintuch S. (eds) Obesity and Diabetes. Springer, Cham. Dec 15, 2020. Pages 137-150 Print ISBN 978-3-030-53369-4
  2. Patel R, Varghese JF, Yadav UCS. Crosstalk Between Adipose Tissue, Macrophages, and Other Immune Cells: Development of Obesity and Inflammation-induced Metabolic Diseases. In: Faintuch J., Faintuch S. (eds) Obesity and Diabetes. Springer, Cham. Dec 15, 2020. Pages 151-163 Online ISBN 978-3-030-53370-0
  3. Patel KR, Chahwala FD, Yada UCS*. Flavonoids as Functional Food. In Yadav UC, Rani V (Eds) Functional Food and Human Health, Springer Nature Singapore Pte Ltd., Singapore, Oct 25, 2018. ISBN 978-981-13-1122-2.
  4. Kumari B, Sharma A, Yadav UCS*. Metabolic Syndrome and Nutritional Interventions. In Yadav UC, Rani V (Eds) Functional Food and Human Health, Springer Nature Singapore Pte Ltd., Singapore, Oct 25, 2018. ISBN 978-981-13-1122-2.
  5. Varghese JF, Patel R, Singh M, Yadav UCS*. Cardiovascular Diseases and Herbal Intervention. In Yadav UC, Rani V (Eds) Functional Food and Human Health, Springer Nature Singapore Pte Ltd., Singapore, Oct 25, 2018. ISBN 978-981-13-1122-2.
  6. Devi A, Reddy ABM, Yadav UCS*.  Aldose Reductase Inhibitors in the Functional Foods: Regulation of Diabetic Complications. In Yadav UC, Rani V (Eds) Functional Food and Human Health, Springer Nature Singapore Pte Ltd., Singapore, Oct 25, 2018. ISBN 978-981-13-1122-2.
  7. Kandhari K, Agraval H, Sharma A, Yadav UCS, Singh RP. Flavonoids and Cancer Stem Cells Maintenance and Growth. In Yadav UC, Rani V (Eds) Functional Food and Human Health, Springer Nature Singapore Pte Ltd., Singapore, Oct 25, 2018. ISBN 978-981-13-1122-2.
  8. Prasad, N, Ramteke, P, Dholia, N and Yadav, UCS*. Therapeutic interventions to block oxidative stress-associated pathologies in S. Chatterjee, W. Jungriathmyr and D. Bagchi (Eds) "Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support", Elsevier Press, New York, NY, Sept 2017, Chapter 27. ISBN (print): 9780128054178
  9. Rani V, Mishra S, Yadav T, Yadav UC, Kohli S. Hydrogen peroxide sensing and signaling. In Yadav UC, Rani V (Eds) “Free Radicals in Human Health and Disease: Oxidative Stress and Human Health”, Springer India (Pvt.) Ltd., New Delhi, India, 2015.  
  10. Rani V, Asthana S, Vadhera M, Yadav UC, Atale N. Tools and techniques to measure oxidative stress. In Yadav UC, Rani V (Eds) Free Radicals in Human Health and Disease: Oxidative Stress and Human Health, Springer India (Pvt.) Ltd., New Delhi, India, 2015.
  11. Dholia N, Ramteke P, Varghese JF, Rani V, Yadav UC*. Oxidative stress induced molecular and genetic mechanisms in human health and diseases. In Yadav UC, Rani V (Eds) Free Radicals in Human Health and Disease: Oxidative Stress and Human Health, Springer India (Pvt.) Ltd., New Delhi, India, 2015.
  12. Vundru SS, Prasad N, Patel R, Rani V, Yadav UC*. Gene-environment interaction in oxidative stress-induced pathologies. In Yadav UC, Rani V (Eds) Free Radicals in Human Health and Disease: Oxidative Stress and Human Health, Springer India (Pvt.) Ltd., New Delhi, India, 2015.
  13. Yadav UC*, Oxidative stress-induced lipid peroxidation: Role in Inflammation. In Yadav UC, Rani V (Eds) Free Radicals in Human Health and Disease: Oxidative Stress and Human Health, Springer India (Pvt.) Ltd., New Delhi, India, 2015.
  14. Yadav UC, Ramana KV. Endotoxin-Induced Uveitis in Rodents. In Irving C Allen (Ed). Mouse Models of Innate Immunity. Methods in Molecular Biology-Methods and Protocols. Humana press, New York, USA. 2013; 1031: 155-162. ISBN (eBook): 978-1-62703-481-4
  15. Reddy AB, Pladzyk A, Yadav UCS, Tammali R, Srivastava SK, Ramana KV. Aldose Reductase Inhibition Prevents Lipopolysaccharide-Induced NF-κB Signaling in Human Lens Epithelial Cells. In Plapp B, Weiner H, Lindahl R, Maser E (Eds). Enzymology and Molecular Biology of Carbonyl Metabolism, Purdue University Press, West Lafayette, Indiana. 30 April 2007; 13: 394-400. ISBN: 13: 9781557534477
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